Acne is an inflammation of the pilosebceous units of certain body areas (face and trunk, rarely buttocks) that occurs most frequently in adolescence.
Duration of lesions is from weeks to month’s .The lesions can be a black heads or white head, papules, papulo-pustules with red or without inflammation, nodules, cyst, atrophic or hypertrophic scars. The goal of therapy, is to remove the plugging of the pilar drainage and to treat the infection with appropriate topical and oral antibiotic, depend on the moderate or severe acne. The Oral Isotretinoin can be indicated in severe, recalcitrant, nodular acne. The nodules should be from 5mm the diameter, many nodules, and with scarring. Also, the patient must have been resistant to other acne therapies, including systemic antibiotics.